Dr. Yousef A. Y. Shamsaldeen

Senior Lecturer in Pharmacology

Dedicated, innovative and initiative pharmacologist with extensive experience across teaching and research in pharmacy and pharmacolog. Excellent experience in research planning and designing, training, supervising, tutoring, and mentoring undergraduate and postgraduate students. In-depth knowledge in lab-based and clinical data research, scientific writing, and statistical analysis. Proven expertise in pharmacology research and collaborative teamwork, demonstrated by publishing research and review papers, and good record in securing research grant and partnership with pharmaceutical and supplement companies. Highly efficient at prioritising work schedules, ensuring efficient administration, and collaborating with multiple teams and stakeholders to ensure academic and institutional goals are met.

WORK HISTORY

  • External Examiner (BSc Pharmacology) | University of Hertfordshire 2026 – Present
  • Senior Lecturer in Pharmacology | Liverpool John Moores University (Co-leader for MPharm course year 1) 2025 – Present
  • Project Consultant | Gulf Health Council January 2025 – August 2025
  • Lecturer in Pharmacology | The University of Brighton (Co-leader for MPharm course year 4) 2022 – 2025
  • Postdoctoral Assistant | St. George’s University of London 2021 – 2022
  • Hospital Pharmacist & Pharmacologist | Kuwait Hospital, Kuwait 2020 – 2021
  • Interim Hospital Pharmacist and Pharmacologist during COVID-19 Pandemic | 2020 – 2021

Al-Adan Paediatric Hospital, Kuwait

  • Hospital Pharmacist & Pharmacologist | Ministry of Health, Kuwait 2019
  • Senior Postdoctoral Research Associate, Department of Physiology, Pharmacology & Neurosciences | 2017 – 2018

University of Bristol

  • Postdoctoral Research Associate, Department of Pharmacy and Pharmacology | University of Bath 2016 – 2017
  • Visiting Lecturer | University of Hertfordshire, School of Life and Biological Sciences 2013 – 2017
  • Quality Assurance quality Control Analyst | LABCO, Kuwait 2012 – 2013

ACADEMIC QUALIFICATION AND TRAINING

  • Fellowship in Higher Education (PR281705) | Advance Higher Education, UK | 2023
  • Associate Fellow (PR269028) | Advance Higher Education, UK | 2023
  • Diploma in Advance Pharmacology | British Pharmacological Society | 2017
  • PhD Pharmacology, Toxicology and Pharmacy | University of Hertfordshire | 2016

Thesis Title “ENDOTHELIAL TRPV4 DYSFUNCTION IN A STREPTOZOTOCIN-DIABETIC RAT MODEL”, examined by Professor Christopher Garland (University of Oxford) and Dr Louise Mackenzie (University of Hertfordshire/University of Brighton).

  • Pharmacology | University of Hertfordshire (UH), UK | 2012
  • Pharmacy | Ajman University of science and technology (AUST), UAE | 2010
  • Diploma in Biomedical Engineering | College of Technology Studies, Kuwait | 2006

 TRAINING:

  • Doctoral Supervisory Training, Liverpool John Moores Univrsity, 2025
  • Doctoral Supervisory Training, University of Brighton, 2023
  • Equality Diversity and Inclusion, University of Brighton, 2023
  • Essential Health and Safety Training, University of Brighton, 2023
  • Data Protection and Information Security Awareness with GDPR, University of Brighton, 2023
  • The Prevent Duty in Higher Education: an introduction, University of Brighton, 2023
  • Student Wellbein, University of Brighton, 2023
  • Pharmacokinetics and Pharmacodynamics, British Pharmacological Society, Liverpool, 2021
  • Pharmacovigilance and risk management, USFDA, 2020.
  • Basic Life Support (Kuwait Medical Training Society, accredited by AHA, 2019).
  • Experimental medicine (Guy’s Hospital, King’s College London, 2017)
  • CREATE scheme’s Courses (University of Bristol, 2017):
    • Student learning and student diversity
    • Lecturing
    • Influencing others
    • Regular productive academic writing
    • Small group teaching
    • Feedback
  • Basic pharmaceutical regulatory affairs (TOPRA, April 2017)
  • Calcium imaging with fluorescence microscopy and flexstation (Wolfson Centre for Age-Related Diseases, King’s College London, 2015)
  • Home office in vivo PIL A-C: 1-4 (Certificate number: BE 2434, 2015)
  • Research programme training sessions at the University of Hertfordshire and University of Bath, including teaching skills, and managing the lecture theatre and classroom climates.
  • Diploma in Advanced Pharmacology. Attended and passed workshops:
    • Bio-imaging (Imperial College London, 2014)
    • General and Advanced Receptor Theory (GART) (Lucy Cavendish, Cambridge, 2014)
    • Statistics (University of Leicester, 2014)
    • Drug Discovery (Hodgkin and Huxley house, Farrington, London, 2014)
    • Enzymes as drug targets (Guy’s hospital, King’s College London, 2014)
    • Integrative and in vivo pharmacology (University of Bristol, 2015)
    • Dissertation: new anti-platelets in collaboration with Dr Melissa Chan from Queen Mary University of London
  • Internship in Global pharma, Dubai. (2010)
  • Clinical pharmacy internship in gulf medical college hospital, Ajman, UAE (2010)
  • Community pharmacy internship in Alhekmah community pharmacy, Ajman, UAE (2010)

ARTICLES AND PUBLICATIONS

ARTICLES

  • Iessa, K., Kalintal, K., Garekyaragh, I., Paget, L., Mangan, Y., Shamsaldeen Y. A., (2026). Immune-Related Adverse Events and Therapeutic Outcomes After Stopping Immune Checkpoint Inhibitors Due to Toxicity Among Patients with Metastatic Melanoma (University Hospitals Sussex). Cancer Medicine. (In press: DOI: 1002/cam4.72119).
  • Trivedi, N., Quraishi, Z., Far, S. K. A., Ward, M., Conway, A., Abdulredha, R., Mshari, E., Shamsaldeen, Y. A. (2026). Dapagliflozin prevents methylglyoxal-induced retinal cell death in ARPE-19 cells. FEBS Open Bio. (https://doi.org/10.1002/2211-5463.70191)
  • Albert, A. P., Janah, K. S., Greenberg, H. Z. E., Shamsaldeen, Y. A. (2024). Role for the PIP2‐binding protein myristoylated alanine rich C‐kinase substrate in vascular tissue: A novel therapeuti target for cardiovascular diseases. J Cell Commun. Signal. https://doi.org/10.1002/ccs3.12052.
  • Victor-Sami, S., Kamali-Roosta, A. and Shamsaldeen, Y. A. (2024). Methylglyoxal Induces Death in Human Brain Neuronal Cells (SH-SY5Y), Prevented by Metformin and Dapagliflozin. Journal of Diabetes and Its Complications. https://doi.org/10.1016/j.jdiacomp.2024.108832.
  • Sabti, M. A, Alajmi, S. and Shamsaldeen, Y. A. (2021). Paediatric poisoning in Kuwait-Al Adan joint hospital: The need for functional poisoning control centre in Kuwait. Saudi Pharmaceutical Journal. https://doi.org/10.1016/j.jsps.2021.10.001.
  • Alsfour, S., Alfailakawi, H. S., and Shamsaldeen, Y. A. (2021). Correcting hypokalaemia in a paediatric patient with Bartter syndrome through an oral dose of potassium chloride intravenous solution, SAGE Open Medical Case Reports (https://doi.org/10.1177/2050313X211019789).
  • Sabti, M. A and Shamsaldeen, Y. A. (2021). Correcting hypophosphataemia in a paediatric patient with Sanjad–Sakati syndrome through a single oral dose of potassium phosphate intravenous solution, SAGE Open Medical Case Reports (https://doi.org/10.1177/2050313X20988412).
  • Shamsaldeen, Y. A., Lione, L. A. & Benham, C. D. (2020). Dysregulation of TRPV4, eNOS and caveolin-1 contribute to endothelial dysfunction in the streptozotocin rat model of diabetes, European Journal of Pharmacology (https://doi.org/10.1016/j.ejphar.2020.173441). This article’s summary has been published on Medicine Innovates
    [    Dysregulation of TRPV4, eNOS and caveolin-1 contribute to endothelial dysfunction – Medicine Innovates]
  • Shamsaldeen, Y. A., Culliford, L., Clout, M., James, A. F., Ascione, R., Hancox, J. C. and Marrion, N. V. (2019). Role of SK channel activation in determining the action potential configuration in freshly isolated human atrial myocytes from the SKArF Study, Biochemical and Biophysical Research Communications (https://doi.org/10.1016/j.bbrc.2019.03.074).
  • Shamsaldeen, Y. A., Alsugoor, Mahdi, H., Lione, L. A. & Benham, C. D. (2019). Dysfunction in nitric oxide synthesis in
    STZ treated rat aorta and role of methylglyoxal, European Journal of Pharmacology (https://doi.org/10.1016/j.ejphar.2018.10.056).
  • Shamsaldeen, Y. A., Ugur, R., Lione, L. A., & Benham, C. D. (2018). Diabetic dyslipidaemia is associated with alterations in eNOS, caveolin-1 and endothelial dysfunction in streptozotocin treated rats. Diabetes/Metabolism Research and Reviews (doi:10.1002/dmrr.2995). This article’s summary has been published on Biomedical Advances [http://biomedical-advances.org/diabetes-201905/]
  • Shamsaldeen, Y. A., Mackenzie, L. S., Lione, L. A., & Benham, C. D. (2016). Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies. Current Drug Metabolism, 17(4), 359-367 (https://doi.org/10.2174/1389200217666151222155216)

CONFERENCE PAPERS:

COFERENCES INVITATIONS:

  • Immune-related adverse events associated with immune checkpoint inhibitors in melanoma patients, as a potential remission marker. Uppsala Monitoring Centre, 25th of September 2025.
  • Observing: A first step for drug discovery. Brighton Sussex Physiological Society Meeting, 22nd of February 2025.

AWARDS AND RECOGNITIONS

  • Inspirational and Motivational Teaching Award, University of Brighton, 2025.
  • Most valuable pharmacist in Kuwait, Provided by PHACT Kuwait: Non-profit organisation in Kuwait, 2020.
  • Best cardio-renal complications oral presentation (University of Hertfordshire Conference), 2014.
  • Third best student oral presentation (Dubai International Pharmaceuticals and Technologies Conference and Exhibition: DUPHAT), 2010.
  • Sixth best student poster presentation (Dubai International Pharmaceuticals and Technologies Conference and Exhibition: DUPHAT), 2010.
  • Best research paper award, Ajman University of Science and Technology Network, 2009.
  • Hosted by live shows on media broadcasting networks in the Middle East to increase medical and pharmaceutical public awareness.

GRANTS AND FUNDING

PUBLIC ACTIVITIES AND VOLUNTEERING

  • General Trustee | British Pharmacological Society 2026 – Present 
  • MPharm students’ guidance and support | Student Union, University of Nottingham 2023
  • Overseas students’ guidance and support | Student Union, University of Nottingham 2022
  • High school students’ guidance and support | Ministry of Education, Kuwait 2019
  • Diabetes UK public awareness campaigns  2013-Present